July 15, 2025 · 5 min
Glycine is a non-essential amino acid vital for protein and collagen synthesis, promoting better sleep and reducing inflammation. Supplementing with 3 to 5 grams before bedtime supports cognitive function, skin, and joint health, making glycine a key ally for lasting vitality and longevity.
Glycine is a non-essential amino acid, meaning your body can produce it on its own. Yet, its importance cannot be overstated. About one-third of collagen—the most abundant protein in the human body—is glycine, making it vital for maintaining healthy skin, joints, and connective tissue. Glycine is also involved in numerous metabolic processes and acts as an inhibitory neurotransmitter in the central nervous system, which helps promote relaxation and improve sleep quality.
Research shows that glycine supplementation before bedtime can improve sleep quality by helping regulate core body temperature and calming the nervous system. Better sleep enhances recovery, mood, and cognitive function essential for high-performing professionals [source].
Glycine modulates neurotransmission and may protect against cognitive decline through anti-inflammatory effects and improved sleep, both critical to maintaining mental sharpness as you age.
Chronic inflammation is a silent driver behind many age-related diseases. Glycine exhibits anti-inflammatory properties that may lower systemic inflammation, thereby supporting cardiovascular and metabolic health.
With glycine composing a large portion of collagen, adequate levels are essential for preserving skin elasticity, preventing wrinkles, and maintaining joint function—keys to physical longevity and mobility.
Clinical studies typically use doses between 3 and 5 grams of oral glycine supplementation to elicit benefits without adverse effects. Taking glycine 30-60 minutes before bedtime is optimal for sleep improvements. High doses beyond 15 grams daily may cause mild gastrointestinal discomfort, so adherence to recommended amounts is advisable.
The National Institutes of Health supports that glycine is generally safe and effective as a supplement within these ranges.
Centenary Day’s web app streamlines supplement decisions and integrates glycine supplementation with personalized routines and nutrition plans. By automating meal planning and biomarker tracking, the platform ensures you maintain optimal glycine levels in conjunction with other nutrients vital for your longevity goals.
For example, linking glycine supplementation with an optimized weekly routine, and monitoring sleep quality and inflammation markers, helps to make health optimization seamless and personalized.
Yes, glycine is generally safe for healthy adults when taken at recommended dosages. However, pregnant or breastfeeding women should consult a healthcare provider before supplementing.
Glycine supports collagen repair and reduces inflammation, which can aid muscle recovery indirectly, although it is not a primary muscle-building amino acid.
Currently, no significant interactions have been documented. Nonetheless, consult your physician if you are taking prescription medications.
Some improvements, like better sleep, may occur within days; however, skin and joint benefits typically require weeks to months of consistent supplementation.
Yes, glycine is abundant in collagen-rich foods like bone broth, gelatin, and meat. Nonetheless, supplementation ensures therapeutic levels without extensive dietary adjustments.
Glycine is a versatile, science-backed supplement that supports sleep quality, cognitive function, inflammation reduction, and collagen production—all fundamental for longevity. By incorporating glycine supplementation into your daily routine and leveraging Centenary Day’s effortless health optimization toolkit, busy professionals can unlock efficient and lasting health benefits without guesswork. Ready to optimize your health the easy way? Get Your Free Personalized Health Plan today and start experiencing the glycine advantage.
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